Scientist, Discovery Bioprocess at BlueRock Therapeutics
New York, US

BlueRock Therapeutics is an engineered cell therapy company with a mission to develop regenerative medicines for intractable diseases. BlueRock’s Cell+Gene platform harnesses the power of cells for new medicines across Neurology, Cardiology and Autoimmunity. BlueRock’s cell differentiation technology recapitulates the cell’s developmental biology to produce native cell therapies, which can be further engineered for additional function. Utilizing these cell therapies to replace damaged or degenerated tissue brings the potential to restore or regenerate lost function. The company was founded in 2016 by Versant Ventures and capitalized with one of the largest-ever Series A financings in biotech history by Bayer AG and Versant.

BlueRock`s ambition is to have an R&D team of dynamic and highly engaged top scientists who are inspired to take project ownership and further develop themselves in one of the most rapidly growing scientific fields. At BlueRock we value open communication, collaboration and a positive and fun working environment in which both individual and team contributions are recognized. Our world-class management team is committed to fostering the growth and career development of employees.

The New York, USA site is seeking a Scientist to join our Discovery Bioprocess team. The incumbent will be a key scientific contributor in a dynamic and progressive team pioneering scaled manufacturing of nervous system cells from pluripotent stem cells. Experience developing mammalian cell culture bioprocesses is essential, familiarity with cGMP manufacturing requirements is a plus.

This is an outstanding opportunity to contribute to bringing a new class of cell-based medicines to patients. Collaboration with a highly-motivated, world-class team of scientists and engineers promises an exciting and engaging work environment for motivated, self-starting candidates.

Position Description:

Design and lead multifaceted projects to characterize and optimize processes for the scalable manufacture of nervous system cells from pluripotent stem cells.

Co-ordinate and interact with other functional areas to ensure a thorough understanding of the impact of scale-up on the quality of the differentiated cell product.

Act as a subject matter expert to support other process development actives, and mentor junior team members.

Analyze experimental data to draw conclusions that support decision-making and next steps within and across projects.

Assist and train others as necessary.

Prepare and present project plans and regular project progress updates and recommendations.

Prepare, review, and approve standard operating procedures, batch records and other process documentation.

Present scientific data to colleagues in group meetings, prepare and present internal and external presentations (presentations, posters, publications), author and submit articles to peer-reviewed journals as required.

Minimum Requirements:

Ph.D. in life sciences or interdisciplinary engineering, OR a Bachelor’s degree plus at least 5 years of experience in the biotechnology/pharmaceutical industry is required

Mammalian cell culture experience is required

Extensive experience with mammalian cell culture, ideally including pluripotent stem cells and differentiation thereof are preferred

Strong background in bioprocessing technologies is preferred

Knowledge of media components and their interactions is a plus.

Experience developing and optimizing cell therapy manufacturing processes a strong plus.

Strong practical knowledge of project planning, experimental design, and statistical analysis of data is required.

Excellent analytical, problem solving, and organizational skills are required.